Nibble is a group of 4 bits. Since each bit can be 0 or 1, a nibble can represent 16 values (from 0000 to 1111 in binary), which is equal to 0 to 15 in decimal or 0 to F in hexadecimal.
Example :
Decimal is 25, then the binary of 25 is 00011001 then the nibbles are as follows Nibbles : High = 0001 (1), Low = 1001 (9)